Any one of these can be applied up to twice daily. For an accurate diagnosis of exfoliative keratolysis, a negative result from a patch test is required. (A study that characterizes the clinical characteristics of 108 atopic dermatitis patients with hand-foot dermatitis. Pits can cluster together to form a sore (lesion) that looks like a crater. Visit your healthcare provider if you have symptoms so they can offer treatment to remove the infection from your body. So, there is actually little room to apply drugs. It may be more common in those with sweaty palms due to localised hyperhidrosis. When your hands are covered in ruptured blisters, the first thing you want to know is the cause of this irritating skin condition. 2020 Dec;34(12):e783-e785. Would you like email updates of new search results? Ultraviolet radiation treatment is also called photochemotherapy (PUVA), and uses ultraviolet rays to treat exfoliative keratolysis. Initially, it doesnt cause any pain or abnormality but gradually some air-filledblisters take over the skin of palms and/or soles. Keratolysis exfoliativa. Antibiotics could include: Clindamycin. She spends her free time reading books and watching TV series. Presently, it is not known to occur from genetic factors, even though a family history is occasionally noted. Acitretin has previously been used to treat diseases of abnormal corneocyte desquamation, for example Netherton's disease. Lets take a brief look at the possible exfoliative keratolysis causes below: One of the first key exfoliative keratolysis symptoms is air-filled blisters that later peel in a circular pattern, or split and form skin tags. government site. Urea is a natural moisturizing factor found in the outer epidermis. Topics AZ It can also fortify the epidermal barrier that may prevent future exfoliative keratolysis outbreaks. After bursting, hand blisters will leave scales that look cracked and reddish. Keratolysis exfoliativa is a condition that is treatable at home. Created for people with ongoing healthcare needs but benefits everyone. - Drug Monographs vol. Firstly, exposure to allergens can cause the condition to develop as it can sometimes be a result of an allergic reaction. When the whole hand and foot peel off it gone for next six months. The Licensed Content is the property of and copyrighted by DSM. Acute exfoliative keratolysis: It is a primary stage of skin peeling of hands. 166. Exfoliative keratolysis. Copyright and all rights reserved. It is also a good idea to avoid the warm weather during the summer, since this can lead to skin peeling that may eventually develop into exfoliative keratolysis. Blisters that form and split at the base of a finger often have deeper cracks that later make the skin feel numb and hard. This can be done by applying the medical ointments like OTC moisturizer on the affected area and then avoiding any water or moisture contact with that affected region. But this method is rarely recommended as psoralen activation works best with UVA. Keratolysis exfoliativa is also characterized by a lack of inflammation. Most patients deny any itching, but may rarely complain of slight tenderness. This is likely a common condition that rarely presents to physicians because it is largely asymptomatic. The latter isnt seasonal as well and happens all year round and is also common for people who have skin asthma. The infection caused by wearing tight or restricting footwear and due to excessive sweating. Mupirocin. After the soak, you can use a pumice stone to remove dry skin from your feet. Acne pitted scar treatment. And because of that, the condition is recurrent as the root problem of the disorder isnt directly addressed. Exfoliative keratolysis Picture 2: Palm with Exfoliative Keratolysis. Recurrent focal palmar peeling. The peeling may be painful in some cases and it is best to get it treated immediately. Antibiotics treat the infection to remove the bacteria from your body. Another reason for skin peeling off is excessive Vitamin A in the body. 8600 Rockville Pike Oatmeal bath this gains improvement when practiced daily, Taking daily Vitamin supplements as weakened immune system predisposes someone to the disorder, Mint application on affected area; mint contains healing properties and has moisturizing effects as well, Pineapple juice applied over to damaged skin, Eating protein rich foods such as meat, liver, carrots as they aid in cell repair, Drinking apple cider vinegar pills and olive extracts, Frequent cutting of fingernails and toenails to maintain hygiene, Avoidance of eating egg as it is a known allergen as well as crustaceans or seafoods. What Is Exfoliative Keratolysis? These ointments and lotions will help reduce the discomfort that causes itching in the skin. The blisters burst to leave expanding collarettes of scale and circular or oval, tender, erythematous peeled areas. Keratolysis exfoliativa. 2016 Oct;107(8):702-4. doi: 10.1016/j.ad.2016.03.006. Lastly, stress can be an important triggering factor for Exfoliative Keratolysis. Lee HJ, Ha SJ, Ahn WK, Kim D, Park YM, Byun DG, Kim JW Pediatr Dermatol 2001 Mar-Apr;18 (2):102-6. doi: 10.1046/j.1525-1470.2001.018002102.x. (Provides a description of the microscopic pattern of splitting seen in keratolysis exfoliativa and contrasts these finding with that of familial continual peeling of the skin), Lee, HJ, Ha, SJ, Ahn, WK, Kim, D, Park, YM, Byun, DG. Pitted keratolysis occurs as a result of a bacterial infection that causes smelly and itchy feet. Fusidic acid. After you start taking an antibiotic, it will begin working within your body to rid it of bacteria. From now on, be watchful towards your health and try these remedies if you ever have exfoliative keratolysis. The condition usually develops in the summer and people with sweaty palms are the first to notice their skin peeling off on their palms. It is also known as Focal Palmar Peeling and is typically observed in young adults Worried about the skin peeling off hands or legs? Acral Peeling Skin Syndrome: A Case Report and Literature Review. There is usually no need for further diagnostic testing, as this is typically a clinical diagnosis; however, in more difficult cases, a potassium hydroxide (KOH) scraping or fungal culture to rule out tinea should be negative and patch testing to rule out allergic contact dermatitis should also be negative. There has been no conventional drug proven to be effective to heal exfoliative keratolysis. Athletes foot is a contagious fungal infection that causes an itchy rash on your feet. As a result, the disorder is already difficult to treat. Keratolysis exfoliativa. The condition is diagnosed when your dermatologist notices peeling skin on palms of hands and cracked skin on fingertips. Wearing shoes with good airflow; avoid rubber boots. Epub 2016 May 18. A diagnosis of Keratolysis Exfoliativa may involve the following exams and procedures: A differential diagnosis may be necessary to eliminate other conditions that present similar signs and symptoms such as: Many clinical conditions may have similar signs and symptoms. Around half of the individuals present the condition in summer months, Individuals with sweaty palms have a higher risk, Exposure to saltwater (especially seawater), Air-filled blister formation on the finger or palm of the hand. There is no definitive cause for Exfoliative Keratolysis, however, there are a couple of situations that make someone susceptible to accumulating the disease. Any of these conditions cause irritation in the skin, resulting in itching and the peeling of the skin. Changing your shoes and socks when they get wet. Your healthcare provider will prescribe topical antibiotics that you rub on your skin like a lotion. The usage of lotions that are rich in Salicylic Acid and Lactic Acid may prevent infection The condition is recurring causing the skin to harden and become rough. The symptoms are aggravated by exposure to irritants including water, soap, detergents and solvents. Then, the blisters burstand it leaves a hollow and blank space underneath the skin. Exfoliative keratolysis is a skin condition that causes the shedding of the top layer of skin. As a result, the skin begins to shred. Use of topical steroids and cortisone cream and even increased levels of prednisone is also effective in treating the problem. In some cases, the following steps may be considered: The following DoveMed website link is a useful resource for additional information: https://www.dovemed.com/healthy-living/skin-disorders/, American Academy of Dermatology930 E. Woodfield Road Schaumburg, IL 60173Phone: (866) 503-SKIN (7546)Fax: (847) 240-1859Website: http://www.aad.org, https://dermnetnz.org/topics/keratolysis-exfoliativa/(accessed on 05/20/2021), https://en.wikipedia.org/wiki/Keratolysis_exfoliativa (accessed on 05/20/2021). (A report of three cases of recurrent focal palmar peeling, of which two were misdiagnosed as chronic dermatitis. 2. In addition, exfoliative keratolysis treatment will include topical steroids and cortisone creams; topical emollients that contain lactic acid, silicone, and urea; photochemotherapy; and a number of home remedies and natural treatments. HHS Vulnerability Disclosure, Help Books about skin diseasesBooks about the skin , 1999. 1. J. Cutan. ), Abdel-Hafez, K, Safer, AM, Selim, MM, Rehak, A. It is possible that sweaty palms are to blame, as hyperhidrosis in the palms is more common. Psoriasis: Psoriasis is a chronic condition that affects the skin. In addition to amino acids and lactic acids, urea is a natural moisturizing factor (NMF) that is commonly found in the outermost layer of . A few cases witness skin peeling on face as well. Recent histopathologic and molecular studies have linked KE to premature corneo-desmosomal disruption. Dermatology Made Easybook. Copyright 2023 Haymarket Media, Inc. All Rights Reserved. If the patients condition worsens or becomes symptomatic, then the diagnosis should be questioned and it may be important to review the differential diagnosis and re-evaluate the patient to rule out other etiologies. Acral skin eruption observed during SARSCoV2 pandemic: possible keratolysis exfoliativa with red palms and soles. Last modified on March 2021With inputs from Dr.Vedalatha Kakani, General Physician. Br J Dermatol. No worries! Pediatr Dermatol. Treat hyperhidrosis if present. For example, rubber boots dont offer sufficient airflow. It also involves the use of Psoralens which are compounds found in plants that also includes methoxsalen, 5-methoxypsoralen and trisoralen. arrow-right-small-blue Please enable it to take advantage of the complete set of features! Some individuals have a family history of the disorder. Once the scales and the redness heals, the condition hibernates. Another is to be extra careful during outbreaks particularly summer season. The following may be helpful: Protection from irritants Emollient hand creams especially those containing urea, lactic acid, or silicone Acitretin Photochemotherapy. The peeled skin from the fingers and fingertips is often harder due to constant peeling before healing takes place. Tinea (typically seen with associated changes in the fingernails or toenails, occasionally pruritic, does not wax and wane, positive fungal scraping or culture, and responds to treatment with antifungal agents). Is the reason for your skin peeling keratolysis exfoliativa Speak to a doctor on MFine and find out how to tackle it! How can you prevent exfoliative keratolysis? Keratolytic creams containing urea, lactic acid, ammonium lactate, or salicylic acid have been the most beneficial treatment for the majority of patients. So, you can say it lasts during the summer. If you notice an odor, along with tiny indentations in the skin on the bottom of your foot, visit your healthcare provider. It can be treated with an application of coconut oil and keep your hand moist. Keratolysis exfoliativa LAST UPDATED: Jul 14, 2021 Introduction Refer to the chapter Peeling skin conditions Disclaimer - the author PCDS cannot accept responsibility for any misleading or incorrect statements, and the management of individual patients remains the direct responsibility of the individual doctor. Exfoliative keratolysis.